Sketching-based Skeleton Extraction

Articulated character animation can be performed by manually creating and rigging a skeleton into an unfolded 3D mesh model. Such tasks are not trivial, as they require a substantial amount of training and practice. Although methods have been proposed to help automatic extraction of skeleton structure, they may not guarantee that the resulting skeleton can help to produce animations according to user manipulation. We present a sketching-based skeleton extraction method to create a user desired skeleton structure which is used in 3D model animation. This method takes user sketching as an input, and based on the mesh segmentation result of a 3D mesh model, generates a skeleton for articulated character animation. In our system, we assume that a user will properly sketch bones by roughly following the mesh model structure. The user is expected to sketch independently on different regions of a mesh model for creating separate bones. For each sketched stroke, we project it into the mesh model so that it becomes the medial axis of its corresponding mesh model region from the current viewer perspective. We call this projected stroke a “sketched bone”. After pre-processing user sketched bones, we cluster them into groups. This process is critical as user sketching can be done from any orientation of a mesh model. To specify the topology feature for different mesh parts, a user can sketch strokes from different orientations of a mesh model, as there may be duplicate strokes from different orientations for the same mesh part. We need a clustering process to merge similar sketched bones into one bone, which we call a “reference bone”. The clustering process is based on three criteria: orientation, overlapping and locality. Given the reference bones as the input, we adopt a mesh segmentation process to assist our skeleton extraction method. To be specific, we apply the reference bones and the seed triangles to segment the input mesh model into meaningful segments using a multiple-region growing mechanism. The seed triangles, which are collected from the reference bones, are used as the initial seeds in the mesh segmentation process. We have designed a new segmentation metric [1] to form a better segmentation criterion. Then we compute the Level Set Diagrams (LSDs) on each mesh part to extract bones and joints. To construct the final skeleton, we connect bones extracted from all mesh parts together into a single structure. There are three major steps involved: optimizing and smoothing bones, generating joints and forming the skeleton structure. After constructing the skeleton model, we have proposed a new method, which utilizes the Linear Blend Skinning (LBS) technique and the Laplacian mesh deformation technique together to perform skeleton-driven animation. Traditional LBS techniques may have self-intersection problem in regions around segmentation boundaries. Laplacian mesh deformation can preserve the local surface details, which can eliminate the self-intersection problem. In this case, we make use of LBS result as the positional constraint to perform a Laplacian mesh deformation. By using the Laplacian mesh deformation method, we maintain the surface details in segmentation boundary regions. This thesis outlines a novel approach to construct a 3D skeleton model interactively, which can also be used in 3D animation and 3D model matching area. The work is motivated by the observation that either most of the existing automatic skeleton extraction methods lack well-positioned joints specification or the manually generated methods require too much professional training to create a good skeleton structure. We dedicate a novel approach to create 3D model skeleton based on user sketching which specifies articulated skeleton with joints. The experimental results show that our method can produce better skeletons in terms of joint positions and topological structure

Sketching-Based Skeleton Generation

Articulated character animation can be performed by manually creating and rigging a skeleton into an unfolded 3D object. Such tasks are not trivial, as it requires a substantial amount of training and practices. Although methods have been proposed to help automatic extraction of skeleton structure, they may not guarantee that the resulting skeleton can help produce desired animations according to user intention. In this paper, we present a sketching-based skeleton generation method suitable for use in the mobile environment. This method takes user sketching as an input, and based on the mesh segmentation result of a 3D object, it estimates a skeleton for articulated character animation. Results show that our method can produce better skeletons in terms of joint positions and topological structure

Motion Retrieval Based on Energy Morphing

Matching and retrieval of motion sequences has become an important research area in recent years, due to the increasing availability and popularity of motion capture data. The main challenge in matching two motion sequences is the diversity of the captured motions, including variable length, local shifting, local and global scaling. Most existing methods employ Dynamic Time Warping (DTW) or Uniform Scaling to handle these problems. In this paper, we propose a novel content-based method for matching of this human motion captured data. We convert the matching problem of motion capture data into a transportation problem. To solve this problem efficiently, we employ Earth Mover’s Distance (EMD) as the matching framework. To penalize any strayed matching, we provide a ground distance that works similar to Sakoe-Chiba band of DTW. Empirical results obtained are encouraging. 1

Can circulating cell free DNA be a promising marker in ovarian cancer? – a genome-scale profiling study in a single institution

Abstract Background Cell-free DNA (cfDNA) is emerging as a potential biomarker for the detection of ovarian cancer (OC). Recently, we reported a method based upon cfDNA whole-genome sequencing data including the nucleosome distribution (nucleosome footprinting NF), terminal signature sequence (motif), DNA fragmentation (fragment), and copy number variation (CNV).In the present study, we explored whether multiomics early screening technology in cfDNA can be applied for early screening of ovarian cancer. Methods Fifty-nine patients with OC and 100 healthy controls were included in this prospective study. Cell-free DNA was extracted from plasma and analyzed by low-pass whole-genome sequencing. Genomic features were obtained for all samples of the cohort, including copy number variation (CNV), 5’-end motifs, fragmentation profiles, and nucleosome footprinting (NF). An integrated scoring system termed the OC score was developed based on the performance of these four features. Results All four features showed diagnostic potential for OC. Based on the unique genome features of cfDNA, the OC score has high accuracy in distinguishing OC patients from healthy controls (AUC 97.7%; sensitivity 94.7%; specificity 98.0%) as a new comprehensive diagnostic method for OC. The OC score showed a gradual trend from healthy controls to OC patients with different stages, especially for early OC monitoring of concern, which achieved a satisfactory sensitivity (85.7%) at a high specificity. Conclusions This is the first study evaluating the potential of cell-free DNA for the diagnosis of primary OC using multidimensional early screening technology. We present a promising method to increase the accuracy of prediction in patients with OC

Coexistence of Multiple Stacking Charge Density Waves in Kagome Superconductor CsV3Sb5{\mathrm{CsV}}_3{\mathrm{Sb}}_5

The recently discovered kagome family ${\mathrm{AV}}_3{\mathrm{Sb}}_5$ (A = K, Rb, Cs) exhibits rich physical phenomena, including non-trivial topological electronic structure, giant anomalous Hall effect, charge density waves (CDW) and superconductivity. Notably, CDW in ${\mathrm{AV}}_3{\mathrm{Sb}}_5$ is evidenced to intertwine with its superconductivity and topology, but its nature remains elusive. Here, we combine x-ray diffraction experiments and density-functional theory calculations to investigate the CDWs in ${\mathrm{CsV}}_3{\mathrm{Sb}}_5$ and demonstrate the coexistence of 2 $\times$ 2 $\times$ 2 and 2 $\times$ 2 $\times$ 4 CDW stacking phases. Competition between these CDW phases is revealed by tracking the temperature evolution of CDW intensities, which also manifests in different transition temperatures during warming- and cooling-measurements. We also identify a meta-stable quenched state of ${\mathrm{CsV}}_3{\mathrm{Sb}}_5$ after fast-cooling process. Our study demonstrates the coexistence of competing CDW stackings in ${\mathrm{CsV}}_3{\mathrm{Sb}}_5$, offering new insights in understanding the novel properties of this system.Comment: 6 pages, 4 figure